2019 Santa Cruz Futebol Clube season

The 2019 season was Santa Cruz's 106th season in the club's history. Santa Cruz competed in the Campeonato Pernambucano, Série C, Copa do Brasil and Copa do Nordeste.

Overall
{| class="wikitable"
 * Games played || 44 (10 Copa do Nordeste, 10 Pernambucano, 6 Copa do Brasil, 18 Série C)
 * Games won || 17 (3 Copa do Nordeste, 5 Pernambucano, 3 Copa do Brasil, 6 Série C)
 * Games drawn || 15 (4 Copa do Nordeste, 3 Pernambucano, 1 Copa do Brasil, 7 Série C)
 * Games lost || 12 (3 Copa do Nordeste, 2 Pernambucano, 2 Copa do Brasil, 5 Série C)
 * Goals scored || 55
 * Goals conceded || 51
 * Goal difference || +4
 * Best results (goal difference) || 4–1 (H) v Afogados da Ingazeira – Pernambucano – 2019.01.29
 * Worst result (goal difference)|| 0–3 (A) v Vitória das Tabocas – Pernambucano – 2019.02.26 0–3 (A) v Ferroviário – Série C – 2019.05.05
 * Top scorer || Pipico (16)
 * Goals conceded || 51
 * Goal difference || +4
 * Best results (goal difference) || 4–1 (H) v Afogados da Ingazeira – Pernambucano – 2019.01.29
 * Worst result (goal difference)|| 0–3 (A) v Vitória das Tabocas – Pernambucano – 2019.02.26 0–3 (A) v Ferroviário – Série C – 2019.05.05
 * Top scorer || Pipico (16)
 * Best results (goal difference) || 4–1 (H) v Afogados da Ingazeira – Pernambucano – 2019.01.29
 * Worst result (goal difference)|| 0–3 (A) v Vitória das Tabocas – Pernambucano – 2019.02.26 0–3 (A) v Ferroviário – Série C – 2019.05.05
 * Top scorer || Pipico (16)
 * Top scorer || Pipico (16)
 * Top scorer || Pipico (16)