2019 Southern Arkansas Muleriders football team

The 2019 Southern Arkansas Muleriders football team represented Southern Arkansas University as a member of the Great American Conference (GAC) during the 2019 NCAA Division II football season. Led by 11th-year head coach Bill Keopple, the Muleriders played their home games at Rip Powell Field at Wilkins Stadium in Magnolia, Arkansas.

Previous season
The Muleriders finished the 2018 season at 8–4 overall and 8–3 in GAC play. They were invited to the Live United Texarkana Bowl, where they lost to, 30–25.

Returning starters
Offense

Defense

Special teams