2020–21 AC Sparta Prague season

The 2020–21 AC Sparta Prague season was the club's 126th season in existence and the 28th consecutive season in the top flight of Czech football. In addition to the domestic league, AC Sparta Prague participated in this season's editions of the Czech Cup and the UEFA Europa League. The season covered the period from 1 August 2020 to 30 June 2021.

First-team squad
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Group stage
The group stage draw was held on 2 October 2020.