2020–21 Empoli FC season

The 2020–21 Empoli Football Club season was the club's 100th season in existence and the club's second consecutive season in the second division of Italian football. In addition to the domestic league, Empoli participated in this season's edition of the Coppa Italia. The season covered the period from 5 August 2020 to 30 June 2021.

The team achieved a remarkable feat by finishing the season unbeaten at home.

Matches
The league fixtures were announced on 9 September 2020.