2020–21 First Women's Basketball League of Serbia

The 2020–21 First Women's Basketball League of Serbia (Прва женска лига Србије 2020–21.) is the 15th season of the First Women's Basketball League of Serbia, the highest professional basketball league in Serbia. Also, it's the 77th national championship played by Serbian clubs inclusive of the nation's previous incarnations as Yugoslavia and Serbia & Montenegro.

Crvena zvezda Kombank won its 32nd national championship.

Promotion and relegation

 * Teams promoted from the Second League
 * Spartak Subotica
 * Art Basket
 * Duga Šabac
 * Teams relegated to the Second League
 * Proleter 023

Playoffs
Four teams were qualified for the Playoffs, as follows: Vojvodina 021, Crvena zvezda Kombank, Radivoj Korać, and Art Basket.

Semifinals

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Finals

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