2020–21 K.V. Oostende season

The 2020–21 K.V. Oostende season was the club's 117th season in existence and its eighth consecutive season in the top flight of Belgian football. In addition to the domestic league, Oostende participated in this season's edition of the Belgian Cup. The season covered the period from 1 July 2020 to 30 June 2021.

Matches
The league fixtures were announced on 8 July 2020.