2020–21 Mid-American Conference women's basketball season

The 2020–21 Mid-American Conference women's basketball season began with practices in October 2020, followed by the start of the 2020–21 NCAA Division I women's basketball season in November. Conference play began in January 2021 and concluded in March 2021. In a season limited due to the ongoing COVID-19 pandemic,  won the MAC regular season championship with a conference record of 14–4. Ohio's Cece Hooks was named MAC player of the year. Second seeded won the MAC tournament with a 77–72 win over Bowling Green. Micaela Kelly was named the tournament MVP. With the automatic bid, Central Michigan was the only MAC school to qualify for the NCAA tournament where they lost to Iowa in the first round. Bowling Green and Ohio accepted bids to the WNIT. Both lost in the first round.

Preseason Awards
The preseason coaches' poll and league awards were announced by the league office on November 19, 2020.

Preseason women's basketball coaches poll
(First place votes in parentheses)
 * 1)  (10) 142
 * 2) Ohio 128
 * 3) Ball State (1) 119
 * 4)  (1) 108
 * 5)  94
 * 6)  88
 * 7)  71
 * 8)  42
 * 9)  41
 * 10)  39
 * 11)  38
 * 12)  28

Tournament Champion: Central Michigan (6), Ohio (3), Buffalo (1), Ball State (1), EMU (1)

Postseason Awards

 * 1) Coach of the Year: Robyn Fralick, Bowling Green
 * 2) Player of the Year: Cece Hooks, Ohio
 * 3) Freshman of the Year: Lexi Fleming, Bowling Green
 * 4) Defensive Player of the Year: Cece Hooks, Ohio
 * 5) Sixth Player of the Year: Janae Poisson, NIU