2020–21 Oxford United F.C. season

The 2020–21 season was Oxford United F.C.'s 127th year in existence and their fifth consecutive season in League One, the third tier of English football. As well as competing in League One, the club also participated in the FA Cup, EFL Cup and EFL Trophy. The season covers the period from 1 July 2020 to 30 June 2021.

Transfers out

 * Notes:

Matches
The 2020–21 season fixtures were released on 21 August.

FA Cup
The draw for the first round was made on Monday 26, October.

EFL Cup
The first round draw was made on 18 August, live on Sky Sports, by Paul Merson. The draw for both the second and third round were confirmed on September 6, live on Sky Sports by Phil Babb.

EFL Trophy
The regional group stage draw was confirmed on 18 August. The second round draw was made by Matt Murray on 20 November, at St Andrew's. The third round was made on 10 December 2020 by Jon Parkin. The draw for the semi-final was announced on 5 February.