2020 Abierto Mexicano Telcel – Women's singles

Heather Watson won the title, defeating qualifier Leylah Annie Fernandez in the final, 6–4, 6–7(8–10), 6–1. It was Fernandez's first WTA Tour final.

Wang Yafan was the defending champion, but lost to compatriot Wang Xiyu in the first round.

Seeds
• #🇺🇸 Sloane Stephens (first round)

• #🇨🇳 Wang Yafan (first round)

• #🇨🇿 Marie Bouzková (first round)

• #🇺🇸 Lauren Davis (first round)

• #🇺🇸 Venus Williams (first round)

• #🇨🇳 Zhu Lin (quarterfinals)

• #🇬🇧 Heather Watson (champion)

• #🇯🇵 Nao Hibino (second round)

Seeds
• # Stefanie Vögele (first round)

• # 🇺🇸 Francesca Di Lorenzo (qualifying competition, lucky loser)

• # 🇦🇺 Lizette Cabrera (first round)

• # Kaja Juvan (qualified)

• # 🇦🇺 Astra Sharma (first round)

• # 🇨🇳 Wang Xiyu (qualified)

• # 🇺🇸 Nicole Gibbs (qualifying competition)

• # 🇺🇸 Usue Maitane Arconada (qualified)

• # 🇺🇦 Anhelina Kalinina (qualifying competition)

• # 🇺🇸 Caroline Dolehide (qualified)

• # 🇪🇸 Lara Arruabarrena (first round)

• # 🇺🇸 Allie Kiick (first round)

Qualifiers
• # 🇮🇹 Sara Errani

• # 🇺🇸 Usue Maitane Arconada

• # 🇨🇦 Leylah Annie Fernandez

• # Kaja Juvan

• # 🇺🇸 Caroline Dolehide

• # 🇨🇳 Wang Xiyu

Lucky loser
• # 🇺🇸 Francesca Di Lorenzo