2020 Amex-Istanbul Challenger – Singles

Ugo Humbert was the defending champion but chose not to defend his title.

Ilya Ivashka won the title after defeating Martin Kližan 6–1, 6–4 in the final.

Seeds
• # 🇪🇸 Pedro Martínez (withdrew)

• # 🇪🇸 Jaume Munar (second round)

• # 🇯🇵 Taro Daniel (first round)

• # 🇷🇺 Evgeny Donskoy (first round, retired)

• # Jason Jung (quarterfinals)

• # 🇮🇹 Lorenzo Giustino (first round)

• # 🇧🇾 Ilya Ivashka (champion)

• # 🇪🇬 Mohamed Safwat (first round)