2020 Internazionali Femminili di Palermo – Singles

Jil Teichmann was the defending champion, but chose not to participate.

Fiona Ferro won the title, defeating Anett Kontaveit in the final, 6–2, 7–5. Ferro became the first player to win a title on the WTA tour following the suspension of the tour due to the COVID-19 pandemic in March 2020.

Seeds
• # Petra Martić (semifinals)

• #🇨🇿 Markéta Vondroušová (first round)

• # Maria Sakkari (first round)

• #🇪🇪 Anett Kontaveit (final)

• #🇧🇪 Elise Mertens (first round)

• # Donna Vekić (second round)

• #🇺🇦 Dayana Yastremska (quarterfinals)

• #🇷🇺 Ekaterina Alexandrova (second round)

Seeds
• # 🇷🇺 Varvara Gracheva (second round)

• # 🇪🇸 Aliona Bolsova (second round)

• # 🇧🇪 Greet Minnen (first round)

• # 🇫🇷 Océane Dodin (qualifying competition, lucky loser)

• # 🇷🇺 Liudmila Samsonova (qualified)

• # 🇧🇾 Aliaksandra Sasnovich (qualified)

• # Kaja Juvan (qualified)

• # 🇧🇪 Ysaline Bonaventure (second round)

Qualifiers
• # Kaja Juvan

• # 🇷🇺 Liudmila Samsonova

• # 🇧🇾 Aliaksandra Sasnovich

• # 🇦🇷 Nadia Podoroska

Lucky loser
• # 🇫🇷 Océane Dodin