2020 LTP Charleston Pro Tennis – Singles

Taylor Townsend was the defending champion, but chose not to participate as she is on maternity leave.

Mayar Sherif won the title, defeating Katarzyna Kawa in the final, 6–2, 6–3.

Seeds
• # 🇺🇸 Shelby Rogers (second round, withdrew)

• # 🇺🇸 Lauren Davis (quarterfinals)

• # 🇺🇸 Madison Brengle (second round)

• # 🇯🇵 Misaki Doi (semifinals, retired)

• # 🇪🇸 Aliona Bolsova (first round)

• # 🇺🇸 Kristie Ahn (first round)

• # 🇩🇪 Anna-Lena Friedsam (first round)

• # 🇺🇸 Ann Li (quarterfinals)