2021–22 Chittagong Abahani season

The 2021–22 season was the Chittagong Abahani's 42nd season since its establishment in 1980 and their 12th season in the Bangladesh Premier League. This also remarked their 8th consecutive season in the top flight after getting promoted in 2014. In addition to domestic league, Ctg Abahani participated on this season's edition of Federation Cup and Independence Cup. The season covered the period from October 2021 to August 2022.

One of the club's new overseas signings, Nigerian striker Peter Ebimobowei scored 22 goals across all the competitions including 20 goals in 2021–22 BPL, making him the first player of the club to score 20 goals in a single Premier League season. Among the other overseas signings of this season, Omid Popalzay was the first Afghan and William Twala was the first South African to represent the club. This was the last season under head coach Maruful Haque.

Group stage
The draw for the group stage was held on 23 November 2021.

Group stage
The draw for the group stage was held on 23 December 2021.

Squad statistics
† Player left Ctg Abahani during the season.