2021–22 FC Nizhny Novgorod season

The 2021–22 season was the seventh season in the existence of FC Nizhny Novgorod and the club's first season in the top flight of Russian football. In addition to the domestic league, FC Nizhny Novgorod participated in this season's editions of the Russian Cup, where they were eliminated in round of sixteen.

Season events
On 16 March, Nizhny Novgorod suspended their contract with Lars Olden Larsen, and terminated their contract with Sylvester Igboun by mutual consent.

Appearances and goals

 * colspan="14"|Players who suspended their contracts:
 * colspan="14"|Players who suspended their contracts:


 * colspan="14"|Players away from the club on loan:
 * colspan="14"|Players away from the club on loan:


 * colspan="14"|Players who appeared for Nizhny Novgorod but left during the season:
 * colspan="14"|Players who appeared for Nizhny Novgorod but left during the season:


 * }

Clean sheets
Anisimov & Sinitsyn both played in Nizhny Novgorod 1-0 victory over Dynamo Barnaul on 22 September 2021