2021–22 FC Red Bull Salzburg season

The 2021–22 season was the 89th season in the existence of the FC Red Bull Salzburg, and the club's 33rd consecutive season in the top flight of the Austrian football. In addition to the domestic league, Salzburg participated in this season's editions of the Austrian Cup and the UEFA Champions League.

Matches
The league fixtures were announced on 22 June 2021.

Play-off round
The draw for the play-off round was held on 2 August 2021.

Group stage
The draw for the group stage was held on 26 August 2021.

Round of 16
The draw for the round of 16 was held on 13 December 2021.