2021–22 Grenoble Foot 38 season

The 2021–22 season was the 111th season in the existence of Grenoble Foot 38 and the club's third consecutive season in the second division of French football. In addition to the domestic league, Grenoble participated in this season's edition of the Coupe de France.

Matches
The league fixtures were announced on 25 June 2021.