2021–22 Heracles Almelo season

The 2021–22 season was the 55th season in the existence of Heracles Almelo and the club's 24th consecutive season in the top flight of Dutch football. In addition to the domestic league, Heracles Almelo participated in this season's editions of the KNVB Cup.

Matches
The league fixtures were announced on 11 June 2021.