2021–22 Iowa Hawkeyes women's basketball team

The 2021–22 Iowa Hawkeyes women's basketball team represented the University of Iowa during the 2021–22 NCAA Division I women's basketball season. The Hawkeyes were led by head coach Lisa Bluder in her twenty-second season, and played their home games at Carver–Hawkeye Arena as a member of the Big Ten Conference.

The Hawkeyes shared the Big Ten regular season title (with Ohio State) and won the 2022 Big Ten tournament to receive an automatic bid to the 2022 NCAA tournament.

On Selection Sunday, Iowa was announced as the number 2 seed for the Greensboro Region, the team's fourth consecutive appearance in the NCAA tournament. The Hawkeyes were upset by 10th-seed Creighton in the second round of the NCAA tournament in a 64–62 loss. They finished the season with a record of 24–8 (14–4 B1G).

Sophomore Caitlin Clark was named Big Ten Player of the Year and a unanimous first-team All-American. Clark became the first player to lead the nation in scoring and assists in the same season.

Previous season
The Hawkeyes finished the 2020–21 season with a 20–10 record, including 11–8 in Big Ten play. They received an at-large bid to the 2021 NCAA Division I women's basketball tournament, where they advanced to the Sweet Sixteen.

Schedule and results
!colspan=9 style=| Exhibition

!colspan=9 style=| Regular Season

!colspan=9 style=| Big Ten Women's Tournament

!colspan=9 style="|NCAA tournament

Rankings
* Coaches did not release a week 1 poll.