2021–22 K.R.C. Genk season

The 2021–22 season was the 34th season in the existence of K.R.C. Genk and the club's 27th consecutive season in the top flight of Belgian football. In addition to the domestic league, Genk participated in this season's editions of the Belgian Cup, the Belgian Super Cup where it finished as runners-up, the UEFA Champions League where it got eliminated in the third qualifying round and in the UEFA Europa League.

Matches
The league fixtures were announced on 8 June 2021.

Group stage
The draw for the group stage was held on 27 August 2021.

Squad appearances and goals

 * Last updated on 21 May 2022.

! colspan=16 style=background:#dcdcdc; text-align:center|Goalkeepers

! colspan=16 style=background:#dcdcdc; text-align:center|Defenders

! colspan=16 style=background:#dcdcdc; text-align:center|Midfielders

! colspan=16 style=background:#dcdcdc; text-align:center|Forwards

! colspan=16 style=background:#dcdcdc; text-align:center|Players who have made an appearance this season but have left the club


 * }