2021–22 Kalamata F.C. season

The 2021–22 season was Kalamata Football Club's 54th in existence and the club's first season in Super League Greece 2, the second level in Greek football, after the 2009–2010 season, when Kalamata was relegated to the amateur leagues.

Pre-season and friendlies
Kalamata's pre-season began on the 2nd of August at Paliambela training ground. From 9 to 22 August Kalamata was training at Portaria were the first friendly of the pre-season against Olympiakos Volou took place. Kalamata won 4–0 with M.Markovski and T.Tselepidis scoring in the first half and new signings G.Loukinas and M.Asamoah scoring in the second.