2021–22 NWFL Premiership

The 2021–22 NWFL Premiership was the 32nd season of the NWFL Premiership, Nigeria's top-flight women's association football league and the second season since its rebranding. The season commenced on 8 December 2021 and ended May 2022.

This season saw a return to the abridged format whereby the fourteen clubs are divided into two groups of seven teams each whereafter a "Super Six" tournament will decide the league champions. Defending champions Rivers Angels finished third at the Championship play-offs.

Bayelsa Queens won their 5th NWFL Premiership title after emerging champions of the Super Six tournament.

Clubs
Naija Ratels and Adamawa Queens were promoted to the top-flight after winning the NWFL Championship play-offs; the latter having failed to compete the previous season due to late licensing and registration. They replaced DreamStar Ladies and Ibom Angels who were relegated after finishing bottom of the group at the previous season's relegation playoffs.

Play-offs
The top six teams at the end of the regular season engaged each other in a round-robin playoff also known as the Super Six between 16 and 22 May in order to decide the league champion and representative at the 2022 CAF Women's Champions League. All matches are played at the Samuel Ogbemudia Stadium and UNIBEN Sports Complex in Benin City.

Top scorers
As of 23 April 2021