2021–22 Nashville Predators season

The 2021–22 Nashville Predators season was the 24th season for the National Hockey League franchise that was established on June 25, 1997. John Hynes entered his third season and second full season as head coach of the team.

The Predators opened the season at home on October 14, 2021, against the NHL's expansion team, the Seattle Kraken. The Predators lost the game 4–3, giving the Kraken the franchise's first-ever win. On April 26, 2022, the Predators clinched a playoff berth after the Dallas Stars defeated the Vegas Golden Knights in a shootout. In the playoffs, the Predators were swept in the first round by the Colorado Avalanche.

Regular season

 * 2021–22 schedule
 * 2021–22 schedule

Player statistics
As of April 30, 2022

Goaltenders
†Denotes player spent time with another team before joining the Predators. Stats reflect time with the Predators only.

‡Denotes player was traded mid-season. Stats reflect time with the Predators only.

Bold/italics denotes franchise record.

Transactions
The Predators have been involved in the following transactions during the 2021–22 season.

Draft picks
Below are the Nashville Predators' selections at the 2021 NHL Entry Draft, which were held on July 23 to 24, 2021. It was held virtually via Video conference call from the NHL Network studio in Secaucus, New Jersey.