2021–22 North Texas Mean Green women's basketball team

The 2021–22 North Texas Mean Green women's basketball team represented the University of North Texas during the 2021–22 NCAA Division I women's basketball season. The team was led by seventh-year head coach Jalie Mitchell, and played their home games at the UNT Coliseum in Denton, Texas as a member of Conference USA (C-USA).

Schedule and results
!colspan=12 style=|Exhibition

!colspan=12 style=|Non-conference regular season

!colspan=12 style=|C-USA regular season

!colspan=12 style=| C-USA tournament

!colspan=12 style=| WNIT

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