2021–22 Olympique de Marseille season

The 2021–22 season was the 116th season in the existence of Olympique de Marseille and the club's 26th consecutive season in the top flight of French football. In addition to the domestic league, Marseille participated in this season's editions of the Coupe de France, the UEFA Europa League and the UEFA Europa Conference League.

Matches
The league fixtures were announced on 25 June 2021.

Group stage
The draw for the group stage was held on 27 August 2021.

Knockout round play-offs
The draw for the knockout round play-offs was held on 13 December 2021.

Round of 16
The round of 16 draw was held on 25 February 2022.

Quarter-finals
The draw for the quarter-finals was held on 18 March 2022.

Semi-finals
The draw for the semi-finals was held on 18 March 2022, after the quarter-final draw.

Appearances and goals
! colspan=14 style=background:#dcdcdc; text-align:center| Goalkeepers

! colspan=14 style=background:#dcdcdc; text-align:center| Defenders

! colspan=14 style=background:#dcdcdc; text-align:center| Midfielders

! colspan=14 style=background:#dcdcdc; text-align:center| Forwards

! colspan=14 style=background:#dcdcdc; text-align:center| Players transferred out during the season