2021–22 R.F.C. Seraing (1922) season

The 2021–22 season will be the 100th season in the existence of R.F.C. Seraing (1922) and the club's first season back in the top flight of Belgian football. In addition to the domestic league, R.F.C. Seraing (1922) will participate in this season's edition of the Belgian Cup.

Matches
The league fixtures were announced on 8 June 2021.