2021–22 Real Valladolid season

The 2021–22 season was the 94th season in the existence of Real Valladolid and the club's first season back in the second division of Spanish football since 2018. In addition to the domestic league, Valladolid participated in this season's edition of the Copa del Rey.

First-team squad
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Matches
The league fixtures were announced on 30 June 2021.