2021–22 Rice Owls men's basketball team

The 2021–22 Rice Owls men's basketball team represented Rice University during the 2021–22 NCAA Division I men's basketball season. The team was led by fifth-year head coach Scott Pera, and played their home games at Tudor Fieldhouse in Houston, Texas as members of Conference USA.

Previous season
The Owls finished the 2020–21 season 15–13, 6–10 in C-USA play to finish in sixth place in West Division. They defeated Southern Miss in first round and Marshall in the second before losing to UAB in the quarterfinals.

Schedule and results
!colspan=12 style=| Exhibition

!colspan=12 style=| Regular season

!colspan=12 style=| Conference USA tournament

!colspan=9 style=| College Basketball Invitational

Source