2021–22 Saint Louis Billikens men's basketball team

The 2021–22 Saint Louis Billikens men's basketball team represented Saint Louis University during the 2021–22 NCAA Division I men's basketball season. Their head coach is Travis Ford in his sixth season at Saint Louis. The team played their home games at Chaifetz Arena as a member of the Atlantic 10 Conference. They finished the season 23–12, 12–6 in A-10 Play to finish in fifth place. They defeated La Salle and St. Bonaventure to advance to the semifinals of the A-10 tournament where they lost to Davidson. They received an at-large bid to the National Invitation Tournament where they lost in the first round to Northern Iowa.

Previous season
In a season limited due to the ongoing COVID-19 pandemic, the Billikens finished the 2020–21 season 14–7, 6–4 in A-10 play to finish in a tie fourth place. They defeated UMass in the quarterfinals of the A-10 tournament before losing to St. Bonaventure in the semifinals. They received an at-large bid of the National Invitation Tournament where they lost to Mississippi State in the first round.

Preseason
In a poll of the league's head coaches and select media members at the conference's media day, the Billikens were picked to finish in third place in the A-10. Javonte Perkins was selected Preseason First Team All-Conference selection while Yuri Collins is a Third Team Preseason honoree. In the preseason game against Rockhurst, Perkins suffered a torn anterior cruciate ligament (ACL) in his left knee and will miss the remainder of the 2021–22 season.

Schedule and results
!colspan=12 style=| Exhibition

!colspan=12 style=| Regular season

!colspan=12 style=| A-10 tournament

!colspan=12 style=| NIT

Source

Rankings
* AP does not release post-NCAA Tournament rankings