2021–22 Serbian First League

The 2021–22 Serbian First League is the 17th season of the Serbian First League since its establishment.

League format
The league consist of 16 teams: eight teams from the 2020–21 Serbian First League, six teams relegated from 2020–21 Serbian SuperLiga and two new teams promoted from Serbian League.

Promotion round
The top eight teams advanced from the regular season. Teams played each other once.

Relegation round
The bottom eight teams from the regular season play in the relegation round. Teams play each other once.

Top scorers
As of matches played on 22 May 2022.

Hat-tricks
4 Player scored four goals