2021–22 South Dakota State Jackrabbits women's basketball team

The 2021–22 South Dakota State Jackrabbits women's basketball represented South Dakota State University in the 2021–22 NCAA Division I women's basketball season. The Jackrabbits, led by 22nd-year head coach Aaron Johnston, compete in the Summit League. They played their home games in Frost Arena in Brookings, South Dakota.

Previous season
The Jackrabbits went 21–4 overall and 14–0 in conference play, finishing first in the Summit League.

South Dakota State lost in the quarterfinals in an upset to #8 seed Omaha, but still qualified for the 2021 NCAA Division I women's basketball tournament as an at-large bid.

In the 2021 NCAA tournament, the Jacks received a nine seed in the River Walk Regional and played Syracuse, to whom they lost 55–72.

Additions
Source:

Schedule
!colspan=9 style=| Exhibition

!colspan=9 style=| Non-conference regular season

!colspan=9 style=| Summit League regular season

!colspan=9 style=| Summit League women's tournament (2–1)

!colspan=9 style=| National Invitational Tournament (5–0)

Source:

Summit League Player of the Week

 * December 27, 2021 – Paige Meyer
 * February 14, 2022 – Myah Selland

Postseason awards

 * Summit League Coach of the Year
 * Aaron Johnston
 * All-Summit League Team
 * Myah Selland, First team
 * Paige Meyer, Second team
 * Paiton Burckhard, Honorable Mention
 * Tylee Irwin, Honorable Mention
 * Tori Nelson, Honorable Mention
 * Summit League All-Defensive Team
 * Tylee Irwin
 * Summit League All-Newcomer Team
 * Paige Meyer
 * WNIT Most Valuable Player
 * Myah Selland
 * WNIT All-Tournament Team
 * Myah Selland
 * Haleigh Timmer