2021–22 Super League Greece 2

The 2021–22 Super League 2, known as Super League 2  betsson for sponsorship reasons, is the third season of the Super League 2, the second-tier Greek professional league for association football clubs, since the restructuring of the Greek football league system.

The season started on 6 November 2021 and ended in May 2022. The league will be conducted of 34 teams and two groups, this is due to the restructure and abolishment of the Football League. The league will also see the introduction of B Teams by Olympiacos, PAOK, AEK Athens and Panathinaikos. B Teams are ineligible for promotion and relegation.

Team changes
The following teams have changed division since the 2020–21 season.

Panachaiki, Ialysos, Santorini 2020, Orfeas Xanthi, Doxa Drama, Panionios, withdrew from the championship.

From Super League Greece 2
Promoted to Super League
 * Ionikos

Relegated to Gamma Ethniki
 * Panachaiki
 * Doxa Drama

To Super League Greece 2
Relegated from Super League
 * AEL

Promoted from Football League
 * Almopos Aridea
 * Apollon Pontus
 * Asteras Vlachioti
 * Egaleo
 * Episkopi
 * Iraklis (replace Triglia)
 * Kalamata
 * Kallithea
 * Kavala
 * Niki Volos
 * Olympiacos Volos
 * Panserraikos
 * Rodos
 * Thesprotos
 * Veria

Promoted from Gamma Ethniki
 * A.E. Kifisia
 * Anagennisi Karditsa
 * Irodotos
 * Zakynthos

B Teams
 * Olympiacos B
 * PAOK B
 * AEK Athens B
 * Panathinaikos B

Title and promotion play-offs
Veria and Levadiakos played a 2 game title play-off on 8 and 15 May 2022.

Top scorers
24 goals


 * 🇬🇷 Giannis Pasas (Veria)

21 goals


 * 🇬🇷 Giannis Loukinas (Kalamata)

20 goals


 * 🇬🇷 Christos Rovas (Almopos Aridea)

17 goals


 * 🇲🇦 Hicham Kanis (Panserraikos)
 * 🇸🇪 Admir Bajrovic (Chania)
 * 🇬🇷 Christos Giousis (AEK Athens B)
 * 🇫🇷 Anthony Mounier (Kallithea)

15 goals


 * 🇬🇷 Alexandros Arnarellis (Egaleo)

14 goals


 * 🇬🇷 Marios Ogkmpoe (AEL)

12 goals


 * 🇦🇷 Nicolás Andereggen (O.F. Ierapetra)

11 goals


 * 🇪🇸 Nili (Levadiakos)
 * 🇬🇷 Andreas Vasilogiannis (Chania)
 * 🇬🇭 Andrews Tetteh (A.E. Kifisia)

10 goals


 * 🇬🇷 Theocharis Pozatzidis (Kallithea/Irodotos)
 * 🇬🇷 Apostolos Sarantidis (Thesprotos)
 * 🇬🇷 Dimitrios Diamantopoulos (Xanthi)
 * 🇬🇷 Georgios Koutsias (PAOK B)
 * 🇨🇲 Rooney Wankewai (Karaiskakis/Apollon Pontou)
 * 🇺🇾 Mathías Tomás (Iraklis)
 * 🇦🇷 Alexis Messidoro (O.F. Ierapetra)

9 goals


 * 🇨🇲 Donaldoni Zambou Nguemechieu (Karaiskakis)
 * 🇨🇾 Nestoras Mytidis (Levadiakos)
 * 🇬🇷 Panagiotis Kynigopoulos (Kallithea)

8 goals


 * 🇬🇷 Petros Giakoumakis (Veria)
 * 🇧🇷 Lucas Poletto (Levadiakos)
 * 🇳🇱 Tyrone Conraad (Ergotelis)
 * 🇷🇸 Bogdan Stamenković (Kavala)
 * 🇵🇾 Wilson Chimeli (Zakynthos)
 * 🇧🇷 Tharcysio (Episkopi)
 * 🇧🇷 Miguel Bianconi (Anagennisi Karditsa)
 * 🇧🇪 Denzel Jubitana (Iraklis)