2021–22 Texas–Rio Grande Valley Vaqueros women's basketball team

The 2021–22 Texas–Rio Grande Valley Vaqueros women's basketball team represents the University of Texas Rio Grande Valley during the 2021–22 NCAA Division I women's basketball season. Lane Lord is in his fourth season as UTRGV's head coach. The Vaqueros play their home games at the UTRGV Fieldhouse and are members of the Western Athletic Conference.

Schedule
!colspan=9 style=| Exhibition

!colspan=9 style=| Non–conference regular schedule

!colspan=9 style=| WAC conference schedule

!colspan=9 style=|WAC Tournament