2021–22 Tottenham Hotspur F.C. Women season

The 2021–22 Tottenham Hotspur F.C. Women season was the club's 37th season in existence and their third in the FA Women's Super League, the highest level of the football pyramid. Along with competing in the WSL, the club also contested two domestic cup competitions: the FA Cup and the League Cup.

Women's FA Cup
As a member of the first tier, Tottenham Hotspur entered the FA Cup in the fourth round proper.

Appearances
''Starting appearances are listed first, followed by substitute appearances after the + symbol where applicable. Players listed with no appearances have been in the matchday squad but only as unused substitutes.''


 * colspan="12"|Players away from the club on loan:
 * colspan="12"|Players away from the club on loan:


 * }

Goalscorers
The list is sorted by shirt number when total goals are equal.

Clean sheets
The list is sorted by shirt number when total clean sheets are equal.