2021–22 UAE President's Cup

The 2021–22 UAE President's Cup was the 45th edition of the UAE President's Cup, Shabab Al Ahli were the defending champions after winning the last season's President's Cup, but were knocked out in the quarter-finals by eventual champions Sharjah.

Preliminary round
The preliminary round is contested between the 16 teams in the UAE First Division League, divided into four groups of four, the winners of each group will advance into a play off round.

Round of 16
All times are local (UTC+04:00)

Top scorers

 * Note: Goals scored in the preliminary round are not included.