2021–22 US Quevilly-Rouen Métropole season

The 2021–22 season was the 120th season in the existence of US Quevilly-Rouen Métropole and the club's first season back in the second division of French football since 2018. In addition to the domestic league, Quevilly-Rouen participated in this season's edition of the Coupe de France.

Matches
The league fixtures were announced on 25 June 2021.