2021–22 US Salernitana 1919 season

The 2021–22 season was the 103rd season in the existence of U.S. Salernitana 1919 and the club's first season back in the top flight of Italian football since 1999. In addition to the domestic league, Salernitana participated in this season's edition of the Coppa Italia.

Matches
The league fixtures were announced on 14 July 2021.