2021–22 Udinese Calcio season

The 2021–22 season was the 125th season in the existence of Udinese Calcio and the club's 27th consecutive season in the top flight of Italian football. In addition to the domestic league, Udinese participated in this season's edition of the Coppa Italia.

Other players under contract
Features player not included in main roster.

Matches
The league fixtures were announced on 14 July 2021.

Appearances and goals
! colspan=14 style=background:#dcdcdc; text-align:center"| Goalkeepers

! colspan=14 style=background:#dcdcdc; text-align:center"| Defenders

! colspan=14 style=background:#dcdcdc; text-align:center"| Midfielders

! colspan=14 style=background:#dcdcdc; text-align:center"| Forwards

! colspan=14 style=background:#dcdcdc; text-align:center"| Players transferred out during the season