2021–22 Uganda Premier League

The 2021–22 Uganda Premier League was the 54th season of the Uganda Premier League, the top-tier football league in Uganda.

Vipers SC won the championship with four games to go, finishing 18 points above second-placed KCCA. Tooro United were also confirmed relegated with four games to go.

Onduparaka FC were docked two points and two goals and were made to replay their December match against KCCA after violence broke out when a penalty was awarded in the 5th minute of extra time.

League Changes
Three teams were promoted from the 2020–21 FUFA Big League, which ended early due to a 42-day lockdown as a result of the COVID-19 pandemic. Arua Hill and Tooro United had already clinched promotion at that point and were promoted. Gaddafi FC were the third team promoted after defeating Proline 2–0 in the final of a four-team playoff held in August 2021.

They replaced Kyetume FC, MYDA, and Kitara, who were relegated from the 2020–21 season.