2021–22 Ukrainian First League

The 2021–22 Ukrainian First League was the 31st since its establishment. The league competition consisted of 16 teams. Earlier in 2021 it was discussed to expand the league to 20 teams with discontinuation of the UPL U-21 competitions, but that initiative was not realized.

The competition was terminated at the PFL Council meeting on 6 May 2022 due to the 2022 Russian invasion of Ukraine.

Teams
This season, Ukrainian First League consisted of 16 teams.

Promoted teams
The following teams have been promoted from the 2020–21 Ukrainian Second League:
 * Podillia Khmelnytskyi – first place in Group A (returning after 22 seasons, however FC Krasyliv that was playing as Podillya Khmelnytskyi last competed in the 2006–07 season)
 * Uzhhorod – second place in Group A (debut)
 * Metalist Kharkiv – first place in Group B (debut, a phoenix club based on the Second League superfinal champions Metal Kharkiv)
 * Kryvbas Kryvyi Rih – second place in Group B (returning after 5 seasons, last competed in the 2015–16 as Hirnyk Kryvyi Rih)

Relegated teams
The following team has been relegated from the 2020–21 Ukrainian Premier League:
 * Olimpik Donetsk – placed 13th (returning after 7 seasons, last competed in the 2013–14)

Renamed teams

 * FC Kramatorsk is a successor of FC Avanhard Kramatorsk which since May 30 was called Avanhard-SK Kramatorsk.
 * FC Metalist Kharkiv is a successor of FC Metal Kharkiv.

Location map
The following displays the location of teams.

Stadiums
The following stadiums were used as home grounds for the teams in the competition. The minimum capacity for stadiums of the First League clubs is set at 1,500 spectators.

Hat-tricks
4 Player scored four goals