2021 ATP Lyon Open – Doubles

Ivan Dodig and Édouard Roger-Vasselin were the defending champions from when the tournament was last held in 2019, but Dodig decided not to participate this year. Roger-Vasselin played alongside Henri Kontinen but lost in the quarterfinals to Matthew Ebden and John-Patrick Smith.

Hugo Nys and Tim Pütz won the title, defeating Pierre-Hugues Herbert and Nicolas Mahut in the final, 6–4, 5–7, [10–8].

Seeds
• # 🇫🇷 Pierre-Hugues Herbert / 🇫🇷 Nicolas Mahut (final)

• # 🇫🇮 Henri Kontinen / 🇫🇷 Édouard Roger-Vasselin (quarterfinals)

• # 🇬🇧 Ken Skupski / 🇬🇧 Neal Skupski (first round)

• # Hugo Nys / 🇩🇪 Tim Pütz (champions)