2021 All Japan University Football Championship

The 2021 All Japan University Football Championship (第70回 全日本大学サッカー選手権大会; All Japan 70th University Football Championship) was the 70th edition of the referred annually contested cup for universities across Japan. As usual, the tournament was contested by 24 universities on a knockout-stage format. Meiji were the defending champions. In this edition, they ended up failing to defend their title, crashing out on the semi-finals by the eventual champions. Komazawa won the title for the seventh time in their 10th participation in finals, and for the first time since 2006. They were the fifth team in a row from Kanto to lift the trophy. Meanwhile, Hannan ended up as runners-up in their second appearance in the tournament's final, as they were also runners-up on 2015.

Participating clubs
In parentheses: Each university's performance at the regional qualifying series.

Schedule
The participating teams and match-ups were disclosed on 21 November 2021.