2021 Amex-Istanbul Challenger – Doubles

Ariel Behar and Gonzalo Escobar were the defending champions but chose not to defend their title.

André Göransson and David Pel won the title after defeating Lloyd Glasspool and Harri Heliövaara 4–6, 6–3, [10–8] in the final.

Seeds
• # 🇮🇱 Jonathan Erlich / 🇧🇾 Andrei Vasilevski (semifinals)

• # 🇸🇪 André Göransson / David Pel (champions)

• # 🇺🇸 Nathaniel Lammons / 🇺🇸 Jackson Withrow (first round)

• # Sander Arends / 🇨🇿 Roman Jebavý (first round)