2021 Australian Open – Wheelchair men's singles

Joachim Gérard defeated Alfie Hewett in the final, 6–0, 4–6, 6–4 to win the men's singles wheelchair tennis title at the 2021 Australian Open.

Shingo Kunieda was the defending champion, but was defeated by Hewett in the semifinals.

Seeds
• # 🇯🇵 Shingo Kunieda (semifinals)

• # 🇦🇷 Gustavo Fernández (quarterfinals)