2021 BBVA Open Internacional de Valencia – Singles

This was the first edition of the tournament.

Martina Trevisan won the title, defeating Dalma Gálfi in the final, 4–6, 6–4, 6–0.

Seeds
• # Arantxa Rus (second round)

• # 🇮🇹 Martina Trevisan (champion)

• # 🇧🇪 Maryna Zanevska (withdrew)

• # 🇧🇬 Viktoriya Tomova (semifinals)

• # 🇷🇴 Irina Bara (quarterfinals)

• # 🇧🇪 Ysaline Bonaventure (first round)

• # 🇭🇺 Dalma Gálfi (final)

• # 🇪🇸 Aliona Bolsova (quarterfinals)