2021 Baltimore Orioles season

The 2021 Baltimore Orioles season was the 121st season in Baltimore Orioles franchise history, the 68th in Baltimore, and the 30th at Oriole Park at Camden Yards. They significantly failed at attempting to improve on their .410 record from the previous year. The Orioles endured two different losing streaks of 14 or more between the middle and the end of May, as well as between August 3 and August 24. The Orioles pitching staff combined for a franchise-worst ERA of 5.84 and yielded 911 earned runs in the season, which led MLB and was the most earned runs surrendered by a pitching staff since the 2001 Texas Rangers allowed 913 earned runs. All of the team's pitchers that made a start finished the season with a losing record. The Orioles were eliminated from playoff contention on August 28 with their loss to the Tampa Bay Rays. They suffered their 3rd 100+ loss season in four years with their loss to the Boston Red Sox on September 17. With the Orioles loss in the season finale against the Blue Jays, they suffered their second 110-loss season in team history; it was also the third such season in overall franchise history, going back to their time as the St. Louis Browns.

Despite the team's atrocious performance, Trey Mancini, who missed the 2020 season with colon cancer, won the AL Comeback Player of the Year award.

Orioles team leaders
Updated through game of October 3. † Minimum 3.1 plate appearances per team games played AVG qualified batters: Mullins, Mountcastle, Mancini, Hays Minimum 1 inning pitched per team games played ERA & WHIP qualified pitchers: No qualifiers

Batting
Note: G = Games played; AB = At bats; R = Runs; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; SB = Stolen bases; BB = Walks; AVG = Batting average; SLG = Slugging average Source:

Pitching
Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; SO = Strikeouts Source:

Achievements

 * John Means pitched a complete game no hitter, defeating the Seattle Mariners 6–0 on May 5.