2021 Boucles de la Mayenne

The 2021 Boucles de la Mayenne was the 46th edition of the Boucles de la Mayenne road cycling stage race, which took place between 27 and 30 May 2021 in the Mayenne department in northwestern France.

The race had been promoted from category-2.1 race to a category-2.Pro race after the 2019 season and was due to be a part of the inaugural edition of the UCI ProSeries, but after the 2020 edition was cancelled due to the COVID-19 pandemic, it made its UCI ProSeries debut in 2021, while also still being a part of the 2021 UCI Europe Tour.

Teams
Five of the nineteen UCI WorldTeams, fourteen UCI ProTeams, and two UCI Continental teams made up the twenty-one teams that participated in the race. and, with five riders each, were the only teams not to enter a full squad of six riders. However, two late scratches, one each from and, left 122 riders on the start line. 111 riders finished the race.

UCI WorldTeams



UCI ProTeams



UCI Continental Teams



Stage 1

 * 27 May 2021 – Le Genest-Saint-Isle to Ambrières-les-Vallées, 175 km

Stage 2

 * 28 May 2021 – Vaiges to Évron, 173 km

Stage 3

 * 29 May 2021 – Saint-Berthevin to Craon, 182 km

Stage 4

 * 30 May 2021 – Méral to Laval, 181 km

Classification leadership table

 * On stage 2, Diego Rubio, who was second in the points classification, wore the green jersey, because first placed Philipp Walsleben wore the yellow jersey as the leader of the general classification.
 * On stage 4, Kristoffer Halvorsen, who was second in the points classification, wore the green jersey, because first placed Arnaud Démare wore the yellow jersey as the leader of the general classification.