2021 Braga Open – Singles

João Domingues was the defending champion but lost in the first round to Jesper de Jong.

Thiago Monteiro won the title after defeating Nikola Milojević 7–5, 7–5 in the final.

Seeds
• # 🇧🇷 Thiago Monteiro (champion)

• # 🇯🇵 Taro Daniel (quarterfinals)

• # 🇫🇷 Hugo Gaston (semifinals)

• # 🇷🇸 Nikola Milojević (final)

• # 🇩🇪 Cedrik-Marcel Stebe (quarterfinals)

• # 🇮🇹 Alessandro Giannessi (second round)

• # Frederico Ferreira Silva (first round)

• # 🇨🇦 Steven Diez (first round, retired)