2021 Budapest Grand Prix – Singles

Simona Halep was the defending champion, having won the previous edition in 2013, but chose not to participate.

Yulia Putintseva won the title, defeating Anhelina Kalinina in the final, 6–4, 6–0.

Seeds
• # 🇰🇿 Yulia Putintseva (champion)

• # 🇺🇸 Danielle Collins (semifinals, retired)

• # 🇺🇸 Bernarda Pera (second round)

• # 🇷🇴 Irina-Camelia Begu (first round)

• # 🇷🇴 Ana Bogdan (second round)

• # 🇧🇾 Aliaksandra Sasnovich (second round)

• # 🇧🇬 Viktoriya Tomova (first round)

• # 🇮🇹 Sara Errani (first round)

Seeds
• # 🇷🇴 Jaqueline Cristian (qualified)

• # 🇷🇸 Olga Danilović (qualified)

• # 🇪🇸 Cristina Bucșa (qualifying competition)

• # 🇪🇸 Lara Arruabarrena (first round)

• # 🇺🇸 Katie Volynets (first round)

• # 🇦🇹 Julia Grabher (qualified)

• # Tereza Mrdeža (qualified)

• # 🇮🇹 Martina Di Giuseppe (qualifying competition; lucky loser)

• # Ekaterine Gorgodze (qualified)

• # 🇺🇸 Jamie Loeb (qualifying competition)

• # 🇩🇪 Katharina Gerlach (first round)

• # 🇺🇦 Kateryna Bondarenko (first round)

Qualifiers
• # 🇷🇴 Jaqueline Cristian

• # 🇷🇸 Olga Danilović

• # Tereza Mrdeža

• # 🇦🇷 Paula Ormaechea

• # Ekaterine Gorgodze

• # 🇦🇹 Julia Grabher

Lucky loser
• # 🇮🇹 Martina Di Giuseppe