2021 Challenge by La Vuelta

The 2021 Ceratizit Challenge by La Vuelta was a women's road cycling stage race that was held in the region of Galicia in northwestern Spain from 2 to 5 September 2021. It was the seventh edition of the Ceratizit Challenge by La Vuelta and was the fifteenth event on the 2021 UCI Women's World Tour calendar. As with previous editions, the final day of the race coincided with the final day of the Vuelta a España.

Teams
All nine UCI Women's WorldTeams and fifteen UCI Women's Continental Teams made up the twenty-four teams that participated in the race. Several teams did not enter a full squad of six riders:, , , , and each entered five riders, while  only entered four. In total, 137 riders started the race, of which 111 finished.

UCI Women's WorldTeams



UCI Women's Continental Teams



Route
The 2021 edition increased the number of stages to 4, with the race finishing in Santiago de Compostela. As usual, the final stage took place in conjunction with the final stage of the 2021 Vuelta a España.

Stage 1

 * 2 September 2021 — Estación de Montaña de Manzaneda to A Rúa, 118.7 km

Stage 2

 * 3 September 2021 — Estación de Montaña de Manzaneda, 7.3 km (ITT)

Stage 3

 * 4 September 2021 — Estación de Montaña de Manzaneda to O Pereiro de Aguiar, 107.9 km

Stage 4

 * 5 September 2021 — As Pontes to Santiago de Compostela, 107.4 km

Classification leadership table

 * On stages 2 and 3, Coryn Rivera, who was second in the points classification, wore the green jersey, because first-placed Marlen Reusser wore the red jersey as the leader of the general classification.