2021 Challenger Ciudad de Guayaquil – Doubles

Luis David Martínez and Felipe Meligeni Alves were the defending champions but only Martínez chose to defend his title, partnering Roberto Quiroz. Martínez lost in the first round to Jesper de Jong and Bart Stevens.

De Jong and Stevens won the title after defeating Diego Hidalgo and Cristian Rodríguez 7–5, 6–2 in the final.

Seeds
• # 🇻🇪 Luis David Martínez / 🇪🇨 Roberto Quiroz (first round)

• # 🇧🇷 Fernando Romboli / 🇧🇴 Federico Zeballos (semifinals)

• # 🇨🇴 Nicolás Barrientos / 🇨🇴 Alejandro Gómez (semifinals)

• # 🇪🇨 Diego Hidalgo / 🇨🇴 Cristian Rodríguez (final)